Figure 7
From: Dysregulation of Blimp1 transcriptional repressor unleashes p130Cas/ErbB2 breast cancer invasion
The interaction between Blimp1 and p130Cas levels positively correlates with the risk of developing multiple metastases. (A) ROC curve representing the prediction results of the logistic regression that discriminates between patients with single or multiple metastases using PRDM1 and BCAR1 expression levels and their interaction as predictors. (B) Effects plots of the regression. A separate plot of the fit is depicted for different levels of BCAR1, from left to right respectively: minimum, 1st quartile, median, 3rd quartile and maximum. In presence of higher expression of BCAR1, the effect of PRDM1 levels on the predicted probabilities becomes positive and progressively larger.
