Table 3 Main effect and interaction of GS with depression status on T2D-related-traits at baseline and follow-up.

From: Influence of depression on genetic predisposition to type 2 diabetes in a multiethnic longitudinal study

 

IFG/IGT status

T2D status

Dysglycemia status

Main Effect

Interaction

Main Effect

Interaction

Main Effect

Interaction

Gene score at Baseline

1.07[1.06–1.08] (5.9 × 10 −26)

1.01[0.98–1.04] (0.55)

1.11 [1.09–1.13] (5.9 × 10 −31)

1.052 [1.01–1.10] (0.026)

1.08[1.07–1.09] (4.7 × 10 −38)

1.02 [0.99–1.05] (0.16)

Gene score at Follow-up

1.05[1.03–1.08] (1.7 × 10 −4)

1.04[0.97–1.12] (0.25)

1.14[1.11–1.17] (2.1 × 10 −20)

1.01[0.94–1.07] (0.86)

1.10[1.07–1.12] (4.0 × 10 −16)

1.02[0.96–1.07] (0.53)

  1. Logistic regression models adjusted for sex, age, BMI and ethnicity.
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