Figure 6 | Scientific Reports

Figure 6

From: Oxidation of protein-bound methionine in Photofrin-photodynamic therapy-treated human tumor cells explored by methionine-containing peptide enrichment and quantitative proteomics approach

Figure 6

The consensus sequence of the oxidized Met-peptides, as analyzed using the iceLogo software. The frequencies of each amino acid at positions surrounding the oxidized Met residues of the 431 oxidized Met-peptides from three PDT conditions were analyzed with the iceLogo software, using a reference database containing all of the non-oxidized Met-peptides identified in our experiments. (a) The high- and low-frequency amino acid residues are shown at upper and lower part of the iceLogo, respectively. The oxidized Met residue is set at position 7. (b) A heat map generated from the same analysis. In both panels, only significantly overrepresented amino acid residues (P < 0.05) are shown.

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