Figure 1

Results of MTT assay and CalcuSyn software analysis for four colorectal cancer cell lines. The groups are defined in “Kanglaite and Taxol treatment”. (A) MTT assay results of two agents and three different treatment combinations. Vertical coordinate represents growth inhibition rate, which is compared with that of untreated cells. Horizontal coordinate represents agent concentrations: the first line is Taxol concentration (nM), the second line is KLT concentration (μg/mL). Points represent the mean from three independent experiments and bars represent standard deviations. (B) CalcuSyn software analysis of the MTT assay results. “CI” - combination index. CI > 1 represents antagonistic cytotoxicity; CI = 1 represents addictive cytotoxicity; CI < 1 represents synergistic cytotoxicity.