Figure 1
From: The role of hydrophobicity in tuberculosis evolution and pathogenicity
The importance of lipid composition and hydrophobicity in the evolution of tubercle bacilli. Abbreviations: PDIMs, phthiocerol dimycocerosates; LOSs, lipooligosaccharides, PGLs, glycosyl phenolphthiocerol dimycocerosates (phenolic glycolipids); DATs & PATs, di- & pentaacyl trehaloses; SGLs, sulfoglycolipids. Graded green and red backgrounds indicate environmental and mammalian pathogen associations, respectively. Evolution cannot take place directly from modern M. kansasii and “M. canettii”, which are shown as related taxa. The hypothetical transitional taxon, labelled “Mycobacterium canettii/tuberculosis”, possibly corresponds to the well-characterised So93R rough variant of “M. canettii”29. Increasing hydrophobicity, with time, applies to both lipid composition and whole cells.
