Table 1 Characteristics of the total study population and by death from cardiovascular disease, breast cancer, and all other cause, within 10 years of diagnosis in Southeast Asian women with breast cancer.
Total study population | Total deaths | Deaths from cardiovascular disease | Deaths from breast cancer | Deaths from all other cause | |
|---|---|---|---|---|---|
n = 5,868 | n = 1,010 | n = 67 (6.8%) | n = 774 (76.6%) | n = 169 (16.7%) | |
Ethnicity, n (%) | |||||
Chinese | 4,663 (79.5) | 740 (73.3) | 50 (6.8) | 555 (75.0) | 135 (18.2) |
Malay | 694 (11.9) | 178 (17.6) | 8 (4.4) | 153 (86.0) | 17 (9.6) |
Indian | 351 (6.0) | 61 (6.0) | 8 (13.1) | 47 (77.0) | 6 (9.9) |
Other* | 160 (2.6) | 31 (3.1) | 1 (3.0) | 19 (61.0) | 11 (35.0) |
Median (IQR) age at diagnosis, years | 52 (45–60) | 56 (47–68) | 69 (58–77) | 53 (45–63) | 65 (54–74) |
Age at diagnosis in groups, n (%) | |||||
<50 | 2530 (43.1) | 346 (34.3) | 9 (2.6) | 312 (90.2) | 25 (7.2) |
50–69 | 2781 (47.4) | 460 (45.5) | 25 (5.4) | 347 (75.4) | 88 (19.1) |
≥65 | 940 (16.0) | 286 (28.0) | 37 (55.0) | 164 (21.0) | 85 (50.0) |
Unknown | 9 (0.0) | 4 (0.0) | 0 (0.0) | 4 (1.0) | 0 (0.0) |
Median (IQR) survival time, years | 6 (3–10) | 3 (2–5) | 4 (2–7) | 3 (2–5) | 3 (2–6) |
Calendar time at diagnosis, n (%) | |||||
1990–1994 | 380 (6.5) | 121 (11.9) | 9 (7.4) | 101 (83.5) | 11 (9.1) |
1995–1999 | 445 (7.6) | 119 (11.8) | 5 (4.2) | 97 (81.5) | 17 (14.3) |
2000–2006 | 1,913 (32.6) | 447 (44.3) | 31 (6.9) | 350 (78.3) | 66 (14.7) |
≥2007 | 3,111 (53.0) | 317 (31.4) | 22 (6.9) | 222 (29.0) | 73 (43.0) |
Unknown | 19 (0.0) | 6 (1.0) | 0 (0.0) | 4 (1.0) | 2 (1.0) |
TNM stage, n (%) | |||||
In situ | 764 (13.0) | 17 (1.7) | 3 (17.6) | 5 (29.4) | 9 (52.9) |
I | 1,381 (23.5) | 91 (9.0) | 9 (9.9) | 49 (53.8) | 33 (36.3) |
II | 2,181 (37.2) | 328 (32.5) | 27 (8.2) | 253 (77.1) | 48 (14.6) |
III | 756 (12.9) | 261 (25.8) | 9 (3.4) | 226 (86.6) | 26 (10.0) |
Unknown | 786 (13.4) | 313 (31.0) | 19 (6.1) | 241 (77.0) | 53 (16.9) |
Tumor differentiation grade, n (%) | |||||
Good | 713 (12.2) | 56 (5.5) | 10 (17.8) | 23 (41.1) | 23 (41.1) |
Moderate | 1,998 (34.0) | 286 (58.0) | 26 (9.1) | 206 (72.0) | 54 (18.9) |
Poor | 2,158 (36.8) | 475 (47.0) | 20 (4.2) | 394 (82.9) | 61 (12.8) |
Unknown | 999 (17.0) | 193 (19.1) | 11 (5.7) | 151 (78.2) | 31 (16.1) |
Estrogen receptor status, n (%) | |||||
Positive | 1,772 (30.2) | 376 (37.2) | 37 (9.8) | 269 (71.5) | 70 (18.6) |
Negative | 2,537 (43.2) | 382 (37.8) | 17 (4.4) | 314 (82.2) | 51 (13.4) |
Unknown | 1,559 (26.6) | 252 (25.0) | 13 (5.2) | 191 (75.8) | 48 (19.0) |
Surgery, n (%) | |||||
Yes | 5,262 (89.7) | 758 (75.0) | 52 (6.9) | 579 (76.4) | 127 (16.8) |
No | 345 (5.9) | 218 (21.6) | 14 (6.4) | 166 (76.1) | 38 (17.5) |
Unknown | 261 (4.4) | 34 (3.4) | 1 (2.9) | 29 (85.3) | 4 (11.8) |
Chemotherapy, n (%) | |||||
Yes | 2,797 (47.7) | 519 (51.3) | 14 (2.7) | 450 (86.7) | 55 (10.6) |
No | 2,671 (45.5) | 453 (44.9) | 52 (11.5) | 293 (64.7) | 108 (23.8) |
Unknown | 400 (6.8) | 38 (3.8) | 1 (2.6) | 31 (81.6) | 6 (15.8) |
Radiotherapy, n (%) | |||||
Yes | 2,735 (46.6) | 462 (45.7) | 20 (4.3) | 383 (82.9) | 59 (12.8) |
No | 2,637 (44.9) | 506 (50.1) | 45 (8.9) | 358 (70.8) | 103 (20.4) |
Unknown | 496 (8.5) | 42 (4.2) | 2 (4.8) | 33 (78.6) | 7 (16.7) |
Hormonal therapy, n (%) | |||||
Yes | 3,355 (57.2) | 537 (53.2) | 44 (8.2) | 393 (73.2) | 100 (18.6) |
No | 2,160 (36.8) | 433 (42.9) | 22 (5.1) | 348 (80.4) | 63 (14.5) |
Unknown | 353 (6.0) | 40 (4.0) | 1 (2.5) | 33 (82.5) | 6 (15.0) |
