Figure 2

Differential protein expression and their cluster analysis of four sample pairwise comparisons. (A) The red and green coloured columns represent up- and down-regulated proteins, and the corresponding number of differentially expressed proteins is indicated. (B) The changing profiles of proteins that were differentially expressed more than 1.2-fold in any one comparison were hierarchically clustered. Different colours represent different expression folds of the proteins. Decreased and increased abundances are indicated by green and red shading, respectively. Each protein group (one per line) is shown along the y-axis, and the comparison groups are shown on the x-axis. Four sample pairwise comparisons were as follows: 1-vs-2, 12 h with 0 mM versus 1 mM Mn(II); 3-vs-4, 48 h with 0 mM versus 1 mM Mn(II); 1-vs-3, 12 h versus 48 h with 0 mM Mn(II); and 2-vs-4, 12 h versus 48 h with 1 mM Mn(II).