Table 1 The proteins involved in the reactive oxygen species scavenging network of MB266.

From: Mechanistic insights into manganese oxidation of a soil-borne Mn(II)-oxidizing Escherichia coli strain by global proteomic and genetic analyses

Enzyme and reaction

Protein or domain

Accession

Description

1-vs-2a

3- vs-4

1- vs-3

2- vs-4

Superoxide and dismutase (SOD) O2  + O2  + 2H+ → H2O2 + O2

SodA

YP_491542.1

Superoxide dismutase, Mn

2.036 b

1.756

1.144

0.967

SodB

YP_489920.1

Superoxide dismutase, Fe

0.677

0.999

0.85

1.202

SodC

YP_489910.1

Superoxide dismutase, Cu, Zn

Catalase 2H2O2 → 2H2O + O2

KatE

YP_489993.1

Hydroperoxidase HPII(III)

0.874

1.155

1.19

1.599

KatG

YP_491509.1

Catalase/hydroperoxidase HPI(I)

1.002

1.062

0.943

1.007

Glutathione reductase (GR) GSSG + NAD(P)H → 2GSH + NAD(P)

Gor

YP_491935.1

Glutathione oxidoreductase

0.934

0.98

1.113

1.091

Glutathione peroxidase (GPX) H2O2 + 2GSH → 2H2O + GSSG

BtuE

YP_489972.1

Glutathione peroxidase

1.128

1.016

1.451

1.288

NADPH oxidase NADPH + e + O2 → NADP + O2  + H+ ROS producer

AhpC

YP_488895.1

Peroxiredoxin, alkyl hydroperoxide reductase

1.049

1.087

0.99

1.087

AhpF

YP_488896.1

Alkyl hydroperoxide reductase, large subunit

1.099

1.152

1.064

1.083

Thioredoxin and thioredoxin reductase H2O2 + Trxred → Trxox + 2 H2O

TrxA

YP_491658.1

Thioredoxin 1

1.254

1.124

1.047

0.993

TrxB

YP_489160.1

Thioredoxin reductase

1.174

0.983

1.292

1.105

YbbN

YP_488783.1

Thioredoxin domain-containing protein

1.067

0.889

1.405

1.163

Ferredoxin

Fdx

YP_490753.1

[2Fe-2S] ferredoxin

1.337

0.672

1.249

0.621

Cytochrome H+  + Cytcred → Cytcox + OH

CyoA

YP_488724.1

Cytochrome c oxidase subunit 2

1.063

0.971

1.01

0.952

CyoB

YP_488723.1

Cytochrome c oxidase subunit 1

1.03

1.122

1.055

1.01

YhjA

YP_491917.1

Cytochrome c peroxidase

1.012

1.217

0.794

0.945

  1. Note: a1-vs-2, 12 h with 0 mM vs. 1 mM Mn (II); 3-vs-4, 48 h with 0 mM vs. 1 mM Mn (II); 1-vs-3, 12 h vs. 48 h with 0 mM Mn (II); and 2-vs-4, 12 h vs. 48 h with 1 mM Mn (II). bBold value represents up-regulated expression (>1.2 fold).