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Figure 1

From: Kai-Xin-San series formulae alleviate depressive-like behaviors on chronic mild stressed mice via regulating neurotrophic factor system on hippocampus

Figure 1

Effect of KXS series formulae treatment on the behaviors of CUMS-treated mice. (A) After four weeks of CUMS treatment, all groups of mice were employed for behavior evaluation tests, including the sucrose preference test, forced swimming test. Fluoxetine at daily dosage of 4 mg/kg was set as the positive control. KXS series treatment was set for three groups, K-652, K-984, D-652, all at 10 g/kg. (B) Non-stressed mice were treated with fluoxetine and KXS. The period and dosage of treatment were same to that of CUMS treated groups. Afterwards, same behavior evaluation tests were applied. Values are expressed in the percentage of non-stressed group as Mean ± SEM (n = 8). Comparisons between groups were carried out by a one-way ANOVA followed by a post-hoc Bonferroni test. #p < 0.05, ##p < 0.01 (compared with non-stressed group); *p < 0.05, **p < 0.01 (compared with stressed group).

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