Figure 1
From: ‘Gardos Channelopathy’: a variant of hereditary Stomatocytosis with complex molecular regulation
(A) LoRRca Osmoscan profile (grey area refers to 150 normal controls); (B) Filterabilty results; healthy cell untreated (Ctr, white bar), pre- incubated with GsMTx-4 (upward hatched bar), TRAM-34 (downward hatched bar) GsMTx-4 + TRAM-34 (dotted bar); patient II.4 (black shaded bar); patient III.1 (grey bar). All measurement were performed at least twice and significance was testes using an unpaired t-test. ** and ***denote p < 0.01 and 0.001 respectively; (C) Separation of RBC on Percoll density gradient and % of cells in low density (L), medium (M) and high (D) density fractions.
