Table 3 Five-year overall and cancer-related survival rates according to the main clinicopathological characteristics, NLR, PLR and PC for the 603 patients under study.

Age

p < 0.001

p = 0.022

 ≤68.9 years

299

85.9

89.4

 >68.9 years

304

64.6

79.3

Gender

p = 0.055

p = 0.052

 Male

347

73.7

82.6

 Female

256

77.2

87.7

Tumour location

p = 0.699

p = 0.818

 Colon

438

74.8

84.1

 Rectum

165

76.1

86.4

Depth of invasion (pT)

p < 0.001

p < 0.001

 pT1

77

89.9

100

 pT2

76

86.5

90.9

 pT3

270

80.8

90.8

 pT4a

122

54.5

65.2

 pT4b

58

55.2

61.5

Node involvement (pN)

p < 0.001

p < 0.001

 pN0

380

81.6

92.5

 pN1

155

71.1

78.6

 pN2

68

44.7

46.9

Systemic metastasis (M)

p < 0.001

p < 0.001

 M0

563

77.8

87.8

 M1a

33

46.5

50.8

 M1b

7

0

0

AJCC/UICC TNM Stage

p < 0.001

p < 0.001

 Stage I

130

89.2

97

 Stage II

237

79.1

91.6

 Stage III

196

68

75.5

 Stage IV

40

37.9

45.8

CEA serum level^a

p < 0.001

p < 0.001

 ≤5 ng/mL

303

78.6

86.1

 >5 ng/mL

92

58.3

73.2

Neutrophil-to-lymphocyte ratio

p < 0.001

p = 0.022

 L-NLR

445

79.8

86.6

 H-NLR

158

62.5

79.4

Platelet-to-lymphocyte ratio

p = 0.070

p = 0.239

 L-PLR

562

75.9

86.6

 H-PLR

41

65.9

79.4

Platelet count

p = 0.122

p = 0.151

 L-PC

453

76.3

85.2

 H-PC

150

71.8

83.5