Table 3 Characteristics of patients according to the presence or absence of bacterial infection at admission.

From: Adipocyte Fatty-Acid Binding Protein is Overexpressed in Cirrhosis and Correlates with Clinical Outcomes

 

Infected (n = 101)

Non-infected (n = 173)

p

Blood leukocytes (109/L)

6.9 (4.5–11.6)

5.4 (3.6–7.8)

0.001

CRP (mg/dL)

3.9 (1.8–6.9)

1.7 (0.7–3.1)

<0.001

IL-6 (pg/mL)

142 (74–272)

89 (45–168)

<0.001

SIRS

51 (51%)

72 (41%)

0.16

Shock

19 (19%)

16 (9%)

0.03

Antibiotic treatment

101 (100%)

57 (33%)

<0.001

MELD score

21 (13–28)

17 (12–22)

0.04

Child-Pugh score

9 (8–12)

9 (7–10)

0.002

MAP (mmHg)

81 (72–88)

83 (76–92)

0.02

Ascites

67 (66%)

116 (67%)

0.9

Hepatic encephalopathy

42 (42%)

44 (25%)

0.004

AKI

56 (55%)

61 (35%)

0.03

ACLF

52 (52%)

61 (35%)

0.011

Development of new infections

21 (21%)

45 (26%)

0.38

A-FABP-4 (ng/mL)

40 (26–89)

36 (18–63)

0.03

L-FABP-1 (ng/mL)

22 (14–37)

27 (18–40)

0.012

I-FABP-2 (ng/mL)

1.3 (0.7–2.1)

0.8 (0.3–1.8)

0.01

  1. Categorical variables are expressed as numbers and percentages (in brackets), continuous variables are expressed as median (inter-quartile range). MELD, model of end stage liver disease; MAP: mean arterial pressure; AKI, acute kidney injury, ACLF: acute-on-chronic liver failure; A-FABP-4: plasma adipocyte fatty acid binding 4; L-FABP-1: plasma liver fatty acid binding 1; I-FABP-2: plasma intestinal fatty acid binding 2.
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