Figure 1 | Scientific Reports

Figure 1

From: Methylglyoxal-induced glycation changes adipose tissue vascular architecture, flow and expansion, leading to insulin resistance

Figure 1

Increased pEAT levels of CEL in HFDMG and GK rats (A), calculated as percentage of Ct, while no differences were observed for GLO-1; representative WB are shown. Glycation increases glycoconjugates, fibrosis and CEL staining in pEAT. Histological analysis shows PAS (100X) (B), Masson Trichrome (100X) (C) and CEL staining (100X) (D). Ct - Wistar 12 m; MG - Wistar + MG supplementation; HFD - HF diet-fed Wistar; HFDMG - HF diet-fed Wistar + MG supplementation; GK - Goto-Kakizaki 12 m. Bars represent means ± SEM, n = 6–8. * vs Ct; $ vs HFD. 1 symbol p < 0.05; 2 symbols p < 0.01.

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