Figure 3
Microglia soma size and roundness. (a) Microglial activity following ONC is associated with an increase in average cell body area; while (b) roundness of the cell soma decreases (one-way ANOVA with Tukey’s post hoc test). These signs of microglial activation are not seen in the retina of the contralateral ONC eyes. (c) Distribution analysis of soma area shows a shift from small to larger cell body sizes after ONC; and (d) distribution analysis of circularity indicates that these cells are more likely to be more irregularly shaped (i.e., to have a lower roundness index). Data are depicted as mean ± 95% confidence intervals.
