Figure 3

Representative photos of histochemical staining images at different time points post-MSC treatment. At day 3, MSC-treatment group had more GFAP+ve cells in the TBI penumbra (3A, IHC x400) and hippocampus (3B IHC x400). More Iba-1+ve cells (3C HIC x400) were observed in the penumbra of MSC-treatment group. Both the penumbra (3D IHC x400) and hippocampus (3D IHC x400) also had higher PCNA expression. MSCs attenuated apoptosis in the hippocampus (3F Tunel, x400). At day 14, more neurons were found in both penumbra and hippocampus of MSC-treatment group (3G Cresyl Violet x400).