Table 4 Risk factors for PJP in acute graft rejection patients (univariate and multivariate analysis).
From: Risk factors for Pneumocystis jirovecii pneumonia (PJP) in kidney transplantation recipients
Variable | Univariate | Multivariate | |||
---|---|---|---|---|---|
PJP negative (n = 97) | PJP positive (n = 15) | P | OR (95% CI) | P | |
Men, sex, N (%) | 62 (63.9) | 13 (86.7) | 0.138 | 6.45 (1.24–33.73) | 0.027 |
Age, years (median, IQR) | 48.0 (38.5–55.0) | 53.0 (43.0–55.0) | 0.128 | 1.03 (0.97–1.10) | 0.331 |
BMI, kg/m2 (median, IQR) | 22.1 (20.2–24.3) | 21.5 (18.6–23.7) | 0.492 | 0.96 (0.77–1.18) | 0.677 |
KT type, living, N (%) | 60 (61.9) | 7 (53.3) | 0.264 | 0.59 (0.18–1.97) | 0.394 |
Ever smoker, N (%) | 27 (27.8) | 5 (13.4) | 0.760 | ||
CMV infection, N (%) | 33 (34.0) | 10 (66.7) | 0.016 | ||
BK virus infection, N (%) | 27 (27.8) | 7 (46.7) | 0.225 | ||
Steroid pulse, N (%) | 97 (100.0) | 15 (100.0) | 1.000 | ||
Using DM medication, N (%) | 34 (35.1) | 7 (46.7) | 0.385 | ||
Using of ATG, N (%) | 38 (39.2) | 11 (73.3) | 0.013 | 5.25 (1.01–27.36) | 0.006 |
Acute graft rejection within 1 year after KT, N (%) | 82 (84.5) | 12 (80.0) | 0.706 | ||
Lowest lymphocyte, 103/μ \(\ell \) (median, IQR) | 0.26 (0.1–0.6) | 0.28 (0.1–0.4) | 0.617 | ||
Rejection number ≥2, N (%) | 28 (28.9) | 6 (40.0) | 0.382 | ||
Re-transplantation, N (%) | 7 (7.2) | 1 (6.7) | 1.000 | ||
History of TB, N (%) | 29 (6.0) | 1 (6.7) | 1.000 | ||
Immunosuppressive agent, N (%) | 1.000 | ||||
Cyclosporine based regimen | 7 (7.2) | 1 (6.7) | |||
Tacrolimus based regimen | 90 (92.8) | 14 (93.3) |