Table 4 Risk factors for PJP in acute graft rejection patients (univariate and multivariate analysis).

From: Risk factors for Pneumocystis jirovecii pneumonia (PJP) in kidney transplantation recipients

Variable

Univariate

Multivariate

PJP negative (n = 97)

PJP positive (n = 15)

P

OR (95% CI)

P

Men, sex, N (%)

62 (63.9)

13 (86.7)

0.138

6.45 (1.24–33.73)

0.027

Age, years (median, IQR)

48.0 (38.5–55.0)

53.0 (43.0–55.0)

0.128

1.03 (0.97–1.10)

0.331

BMI, kg/m2 (median, IQR)

22.1 (20.2–24.3)

21.5 (18.6–23.7)

0.492

0.96 (0.77–1.18)

0.677

KT type, living, N (%)

60 (61.9)

7 (53.3)

0.264

0.59 (0.18–1.97)

0.394

Ever smoker, N (%)

27 (27.8)

5 (13.4)

0.760

  

CMV infection, N (%)

33 (34.0)

10 (66.7)

0.016

  

BK virus infection, N (%)

27 (27.8)

7 (46.7)

0.225

  

Steroid pulse, N (%)

97 (100.0)

15 (100.0)

1.000

  

Using DM medication, N (%)

34 (35.1)

7 (46.7)

0.385

  

Using of ATG, N (%)

38 (39.2)

11 (73.3)

0.013

5.25 (1.01–27.36)

0.006

Acute graft rejection within 1 year after KT, N (%)

82 (84.5)

12 (80.0)

0.706

  

Lowest lymphocyte, 103/μ \(\ell \) (median, IQR)

0.26 (0.1–0.6)

0.28 (0.1–0.4)

0.617

  

Rejection number ≥2, N (%)

28 (28.9)

6 (40.0)

0.382

  

Re-transplantation, N (%)

7 (7.2)

1 (6.7)

1.000

  

History of TB, N (%)

29 (6.0)

1 (6.7)

1.000

  

Immunosuppressive agent, N (%)

  

1.000

  

 Cyclosporine based regimen

7 (7.2)

1 (6.7)

   

 Tacrolimus based regimen

90 (92.8)

14 (93.3)

   
  1. Abbreviations: PJP, Pneumocystis jirovecii pneumonia; OR, Odds ratio; CI, confidence interval; IQR, interquartile range; BMI, body mass index; KT, kidney transplantation; DM, diabetes mellitus; ATG, anti-thymocyte globulin; TB, tuberculosis.