Figure 2
From: Intradermal administration of IL-33 induces allergic airway inflammation
Intradermal administration of IL-33 aggravates airway inflammation and mucus secretion in experimental asthma. (a) Experimental protocol. (b) Cell counts in the BAL fluid. The significance between two groups was determined by two-tailed Student’s t test. (c) OVA-specific IgE on Day 25. (d) Representative lung tissue cross-sections stained with PAS to visualize mucus-producing goblet cells and airway inflammation. Left, PBS + OVA; Right, IL-33 + OVA. Bar, 100 µm. T, total cells; E, eosinophils; M, macrophages; N, Neutrophils; L, lymphocytes. Data are representative of two independent experiments with five mice per group. Error bars indicate the mean ± SD. ***p ≤ 0.001.
