Figure 1

The OSI was significantly elevated in antihypertensive-treated SHRs compared with WKYs. (a) Contour plots of the OSI values averaged over one cardiac cycle analysed from aorta models in SHRs and WKYs. The OSI scale ranges from 0 (dark blue) to 0.5 (red). (b) The ratio of the area with an OSI > 0.2 of the whole geometry and (c) the OSI values in a region near the inner wall of the aortic arch are shown. Values are presented as the mean ± SD. (n = 6). *P < 0.05, **P < 0.01, ***P < 0.001, vs WKY-CON. ## P < 0.01, vs SHR-CON. † P < 0.05, ††† P < 0.001, vs WKY-NIF. CON, control; NIF, nifedipine.