Table 2 Association between genotypes of PICK1 and clinical symptoms in schizophrenic patients.

From: PICK1 Genetic Variation and Cognitive Function in Patients with Schizophrenia

Cognitive domain

rs2076369

rs3952

TT

GT

GG

p

AA

AG

GG

p

PANSS total

89.86 (17.109)

83.78 (13.289)

85.23 (12.510)

0.439

83.91 (14.433)

86.20 (13.316)

83.75 (10.608)

0.552

PANSSa-positive subscale

20. 86 (5.651)

19.39 (4.582)

20.11 (4.375)

0.504

19.28 (4.974)

20.20 (4.448)

20.07 (4.057)

0.265

PANSS-negative subscale

26.52 (7.097)

23.73 (5.174)

23.52 (4.709)

0.119

24.24 (5.882)

24.01 (5.085)

22.62 (3.580)

0.125

SANSb 20-total

55.67 (18.315)

50.57 (16.209)

50.43 (15.382)

0.357

51.09 (16.350)

51.46 (16.713)

48.98 (13.149)

0.590

  1. All data were presented by mean (standard deviation).
  2. According to normality of data, Analysis of Variance (ANOVA) was used for SANS 20-total and Kruskal-Wallis test for other items.
  3. aPANSS = Positive and Negative Syndrome Scale.
  4. bSANS = Scale for the Assessment of Negative Symptoms.
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