Table 2 Univariate and multivariate Cox regression analyses of PFS in 36 enrolled adult Xp11.2 RCC patients.
From: PD-L1 expression in Xp11.2 translocation renal cell carcinoma: Indicator of tumor aggressiveness
Covariates | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
HR (95% CI) | P value | HR (95% CI) | P value | |
Age at surgery | 1.0 (0.9–1.0) | 0.068 | ||
Sex (male vs. female) | 0.6 (0.3–1.5) | 0.297 | ||
Clinical manifestation (incidental vs. symptomatic) | 0.9 (0.4–2.2) | 0.888 | ||
Laterality (left vs. right) | 1.2 (0.5–2.7) | 0.725 | ||
Surgical option (radical vs. partical) | 0.4 (0.1–1.6) | 0.186 | ||
Tumor size | 1.1 (0.9–1.2) | 0.324 | ||
T stage (T1-T2 vs. T3-T4) | 3.8 (1.5–9.8) | 0.005 | 2.5 (0.8–7.6) | 0.097 |
N stage (N0 vs. N1) | 5.6 (2.0–15.5) | 0.001 | 4.0 (1.2–13.7) | 0.025 |
M stage (M0 vs. M1) | 13.7 (3.5–54.4) | <0.001 | 9.6 (2.0–45.0) | 0.004 |
ISUP grade (2 vs. 3 or 4) | 0.6 (0.2–1.9) | 0.375 | ||
PD-L1 expression (negative vs. positive) | 4.7 (1.7–13.0) | 0.003 | 3.7 (1.3–10.9) | 0.018 |
