Figure 2 | Scientific Reports

Figure 2

From: Role of FoxO1 and apoptosis in pulmonary vascular remolding in a rat model of chronic thromboembolic pulmonary hypertension

Figure 2

Pathological changes in the pulmonary artery in the rat CTEPH model. Note: No significant changes in the pulmonary artery were detected in the sham group (A). One hour after injection, pathological changes included connective tissue organization surrounding the reddish-brown thrombus (B); the thrombus (C) was smllar in the 1-week experimental subgroup. At 4-weeks, increased growth of pulmonary artery endothelial layer were detected (D,E). Vimentin and FVIII factor in sham group (F), 1-week (G) and 2-week (H) experimental subgroup. Red light: FVIII factor (white arrows), green light: vimentin (yellow arrows), blue light: nuclear.

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