Figure 5 | Scientific Reports

Figure 5

From: Both haemagglutinin-specific antibody and T cell responses induced by a chimpanzee adenoviral vaccine confer protection against influenza H7N9 viral challenge

Figure 5

Antibody responses in guinea pigs. Twelve female guinea pigs were divided into 4 groups: the AdC68-H7HA group, the pCAGGS-H7HA group, the AdC68-gp group, and the prime-boost group. Guinea pigs were administered doses double those in mice. Serum samples were collected every 2 weeks for antibody detection. (a) Total IgG in guinea pigs taken at different times after immunization. (b) HAI titres in guinea pigs at 4, 8, and 12 weeks after immunization. (c) NT titres in guinea pigs at 4, 8, and 12 weeks after immunization. ***p < 0.001; **p < 0.01; *p < 0.05. #At two weeks post immunization, the prime-boost group received DNA priming, as in the DNA-only group.

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