Figure 3
From: Prognostic relevance of UCH-L1 and α-internexin in pancreatic neuroendocrine tumors
Promoter methylation of UCH-L1 in cancer cell lines and PNETs. The methylation of UCH-L1 promoter was more common in tumors without expression of UCH-L1 protein and para-tumor tissues (#289 N, #88 N). Demethylation was frequently seen in tumours with UCHL1 expression. U: unmethylated; M: methylated. Cell lines SW480 and SH-SY5Y were used as methylation and unmethylation controls, respectively, and TE buffer as blank control. Sequencing PCR products confirmed the MSP results.
