Figure 1 | Scientific Reports

Figure 1

From: Cancer cachexia associates with a systemic autophagy-inducing activity mimicked by cancer cell-derived IL-6 trans-signaling

Figure 1

Blood samples from cancer patients with weight loss harbor autophagy-inducing bioactivity. (a) Autophagy flux in reporter cells exposed to sera from lung cancer patients (n = 79) or healthy controls (n = 148) (Student t-test). (b) Weight loss (% loss during 3 months prior to blood sampling) in lung cancer patients and autophagy-inducing activity in their sera, measured using an autophagy reporter cells system. (c) Weight loss (% loss during 6 months prior to blood sampling) in GI cancer patients and autophagy-inducing activity in their plasma, measured using an autophagy reporter cells system. (d,e) As in (b), but divided by gender.

Back to article page