Figure 6 | Scientific Reports

Figure 6

From: Alpha7 nicotinic acetylcholine receptor agonist promotes retinal ganglion cell function via modulating GABAergic presynaptic activity in a chronic glaucomatous model

Figure 6

PNU-282987 prevents the reduction in GAD65/67 protein expression caused by chronic ocular hypertension. (A) Western blotting showing the effects of PNU-282987 on GAD65/67 protein expression in glaucomatous retina. The full-length blots are presented in Supplementary Figure S1. (B) Densitometric analysis of GAD65/67 confirming that PNU-282987 upregulates GAD65/67 protein expression in glaucomatous retina (n = 6). *p < 0.05 (Student’s paired t test). GAD65/67 expression was normalized to β-actin and is shown relative to its expression in control retinas. The results in B are expressed as the mean ± SE. GAD, glutamic acid decarboxylase.

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