Table 3 Average ± standard deviation for the structural features extracted from MRI that showed statistically significant differences between healthy controls and ET patients.

From: A data mining approach using cortical thickness for diagnosis and characterization of essential tremor

Features

Healthy controls (N = 18)

Essential tremor patients (N = 18)

Student’s t test or Mann-Whitney U test, Bonferroni corrected

lh-hippocampus-volume/ICV

0.0026 ± 0.0005

0.0023 ± 0.0003

t(34) = 2.185, p = 0.036

lh-entorhinal-volume

2072 ± 339

1762 ± 523

t(34) = 2.113, p = 0.042

lh-superiorfrontal-thickness

2.6867 ± 0.1166

2.5888 ± 0.1429

t(34) = 2.253, p = 0.031

lh-lateralorbitofrontal-thickness

2.6403 ± 0.1120

2.5516 ± 0.1264

t(34) = 2.229, p = 0.033

lh-precentral-thickness

2.5486 ± 0.1114

2.4398 ± 0.1394

t(34) = 2.585, p = 0.014

lh-supramarginal-thickness

2.5972 ± 0.1389

2.5018 ± 0.1396

t(34) = 2.054, p = 0.048

lh-temporal lobe-thickness

2.9744 ± 0.1273

2.8529 ± 0.1711

t(34) = 2.418, p = 0.021

lh-superior temporal-thickness

2.8380 ± 0.1419

2.7027 ± 0.2043

t(34) = 2.307, p = 0.027

lh-temporal pole-thickness

3.8554 ± 0.3878

3.6003 ± 0.3466

t(34) = 2.081, p = 0.045

lh-rostral anterior cingulate-thickness

2.9302 ± 0.2321

2.7606 ± 0.2121

U = 85.5, p = 0.014

lh-posterior temporal-roughness

0.4572 ± 0.0601

0.5017 ± 0.0697

t(34) = −2.049, p = 0.048

lh-temporal pole-roughness

0.7118 ± 0.1529

0.8158 ± 0.0990

t(34) = −2.420, p = 0.021

lh-posterior cingulate-roughness

0.5903 ± 0.0793

0.6474 ± 0.0865

t(34) = −2.067, p = 0.046

rh-superiorfrontal-thickness

2.6792 ± 0.1192

2.5441 ± 0.1372

t(34) = 2.455, p = 0.019

rh-precentral-thickness

2.5302 ± 0.1072

2.4322 ± 0.1447

t(34) = 2.308, p = 0.027

rh-temporal lobe-thickness

3.0075 ± 0.1223

2.9078 ± 0.1568

t(34) = 2.128, p = 0.041

rh-superior temporal-thickness

2.8262 ± 0.1460

2.7007 ± 0.1932

t(34) = 2.198, p = 0.035

rh-temporal pole-thickness

3.9693 ± 0.2767

3.7626 ± 0.3186

t(34) = 2.078, p = 0.045

rh-parahippocampal-thickness

2.8016 ± 0.2811

2.6067 ± 0.2033

t(34) = 2.383, p = 0.023

rh-entorhinal-roughness

0.7413 ± 0.1244

0.8305 ± 0.1212

t(34) = −2.180, p = 0.036

  1. Values are expressed as mean ± standard deviation. Student’s t test was used for parametric comparisons and Mann Whitney test for non parametric comparisons. lh: left hemisphere; rh: right hemisphere; ICV: Intracranial volume.