Table 3 Average ± standard deviation for the structural features extracted from MRI that showed statistically significant differences between healthy controls and ET patients.
Features | Healthy controls (N = 18) | Essential tremor patients (N = 18) | Student’s t test or Mann-Whitney U test, Bonferroni corrected |
---|---|---|---|
lh-hippocampus-volume/ICV | 0.0026 ± 0.0005 | 0.0023 ± 0.0003 | t(34) = 2.185, p = 0.036 |
lh-entorhinal-volume | 2072 ± 339 | 1762 ± 523 | t(34) = 2.113, p = 0.042 |
lh-superiorfrontal-thickness | 2.6867 ± 0.1166 | 2.5888 ± 0.1429 | t(34) = 2.253, p = 0.031 |
lh-lateralorbitofrontal-thickness | 2.6403 ± 0.1120 | 2.5516 ± 0.1264 | t(34) = 2.229, p = 0.033 |
lh-precentral-thickness | 2.5486 ± 0.1114 | 2.4398 ± 0.1394 | t(34) = 2.585, p = 0.014 |
lh-supramarginal-thickness | 2.5972 ± 0.1389 | 2.5018 ± 0.1396 | t(34) = 2.054, p = 0.048 |
lh-temporal lobe-thickness | 2.9744 ± 0.1273 | 2.8529 ± 0.1711 | t(34) = 2.418, p = 0.021 |
lh-superior temporal-thickness | 2.8380 ± 0.1419 | 2.7027 ± 0.2043 | t(34) = 2.307, p = 0.027 |
lh-temporal pole-thickness | 3.8554 ± 0.3878 | 3.6003 ± 0.3466 | t(34) = 2.081, p = 0.045 |
lh-rostral anterior cingulate-thickness | 2.9302 ± 0.2321 | 2.7606 ± 0.2121 | U = 85.5, p = 0.014 |
lh-posterior temporal-roughness | 0.4572 ± 0.0601 | 0.5017 ± 0.0697 | t(34) = −2.049, p = 0.048 |
lh-temporal pole-roughness | 0.7118 ± 0.1529 | 0.8158 ± 0.0990 | t(34) = −2.420, p = 0.021 |
lh-posterior cingulate-roughness | 0.5903 ± 0.0793 | 0.6474 ± 0.0865 | t(34) = −2.067, p = 0.046 |
rh-superiorfrontal-thickness | 2.6792 ± 0.1192 | 2.5441 ± 0.1372 | t(34) = 2.455, p = 0.019 |
rh-precentral-thickness | 2.5302 ± 0.1072 | 2.4322 ± 0.1447 | t(34) = 2.308, p = 0.027 |
rh-temporal lobe-thickness | 3.0075 ± 0.1223 | 2.9078 ± 0.1568 | t(34) = 2.128, p = 0.041 |
rh-superior temporal-thickness | 2.8262 ± 0.1460 | 2.7007 ± 0.1932 | t(34) = 2.198, p = 0.035 |
rh-temporal pole-thickness | 3.9693 ± 0.2767 | 3.7626 ± 0.3186 | t(34) = 2.078, p = 0.045 |
rh-parahippocampal-thickness | 2.8016 ± 0.2811 | 2.6067 ± 0.2033 | t(34) = 2.383, p = 0.023 |
rh-entorhinal-roughness | 0.7413 ± 0.1244 | 0.8305 ± 0.1212 | t(34) = −2.180, p = 0.036 |