Figure 1 | Scientific Reports

Figure 1

From: Organoid-based epithelial to mesenchymal transition (OEMT) model: from an intestinal fibrosis perspective

Figure 1

Disruption of IEOs by TGF-β1 treatment. (A) Cellular components of IEOs were stained with various cell markers constituting the intestinal epithelium. Bars, 50 μm. (B) Representative images showing IEOs treated with or without TGF-β. Bars, 100 μm. (C) Concentration-dependency of the TGF-β1-mediated IEO disruption. The number of live and disrupted organoids was counted by concentration after 48 hours TGF-β1 treatment. (D) Time-dependency of the TGF-β1-mediated IEO disruption. The number of live and disrupted organoids was counted by time after the treatment. Data are presented as the mean ± SEM; n = 3 samples per bar.

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