Figure 2

Variable effects of oral administration of five probiotic LAB strains on protection against ST-induced allergic reactions in mice. Time-course of ST-specific IgE (A) and IgG1 (B) antibodies in sera were determined by ELISA. (C) Histamine levels in sera collected at the second challenge on day 61were analyzed, and symptom scores were recorded during a 1-h observation period after challenge. The error bars indicate standard deviation (±SD). Statistical significance (p < 0.05) was marked by different letters in histamine level analysis. *p < 0.05, **p < 0.01, ***p < 0.001.