Figure 7 | Scientific Reports

Figure 7

From: Lactic acid bacteria-specific induction of CD4+Foxp3+T cells ameliorates shrimp tropomyosin-induced allergic response in mice via suppression of mTOR signaling

Figure 7

Treatment with Bc mediates mTOR signaling blockade leading to up-regulation of Foxp3 expression. (A) Splenocytes were lysed and immunoblotted with antibodies to SGK1phospho Ser422, pan-Aktphospho T305/308/309, p70S6Kphospho Thr389, 4E-BP1phospho Thr37/46, Aktphospho Ser473, Stat3phospho Tyr705, Foxp3, p70S6K, 4E-BP1, Akt, SGK1, GATA3 and β-actin. (B) Quantitation of band intensities are shown, respectively. (C) The levels of mTOR were analyzed by ELISA. The results shown are representative of more than three experiments with similar results. Data are expressed as means ± SD. n. s., no significance. Full-length blots are presented in Supplementary Fig. S9.

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