Table 1 Comparison of the brightnesses of free AF488 dye and AF488-C(0)Aβ42 in 0.25 M and 5 M GdnHCl solution obtained from PCH analysis (Fig. 2).

From: Fluorescence correlation spectroscopy reveals a cooperative unfolding of monomeric amyloid-β 42 with a low Gibbs free energy

sample

AF488

AF488-C(0)Aβ42

GdnHCl conc. [M]

0.25

5

0.25

5

brightness [kHz]

16.23 (±0.22)

6.36 (±0.43)

18.73 (±2.23)

6.32 (±0.18)