Figure 5 | Scientific Reports

Figure 5

From: The Plasmodium PI(4)K inhibitor KDU691 selectively inhibits dihydroartemisinin-pretreated Plasmodium falciparum ring-stage parasites

Figure 5

Clinical isolates of DP-rings are susceptible to KDU691. (A) Rings and (B) DP-rings. Data were normalized to (A) DMSO-treated rings and (B) DMSO-treated DP-rings. Measurements were taken by HCI using MitoTracker® Orange at day three for rings and day six for DP-rings. KDU691 was added at a concentration of 1.4 µM. Data are from three biological experiments and two technical replicates each (means ± SEM % growth). Percent growth was measured by HCI using MitoTracker® Orange relative to DMSO.

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