Figure 7
Metabolite profiles in young and aged aak-2 mutants. (a) In early adulthood (day 1), the abundance of FAs in aak-2(ok524) was similar to N2 worms. (b) While most FAs accumulated in aged N2 worms (day 7), this accumulation was attenuated in aged aak-2(ok524) worms, suggesting that this gene drives the observed age-related changes in lipid metabolism. Bar graphs are expressed as mean ± SD, Significance was calculated using Student’s t-test. *p ≤ 0.05; **p ≤ 0.01; ***p ≤ 0.001; ****p ≤ 0.0001.
