Figure 2
From: Use of genetically modified bacteria for drug delivery in humans: Revisiting the safety aspect
Schematic representation of 3 possible cblA gene duplication scenarios: (a) insertion of duplicated cblA gene into random position of chromosome, (b) diploid bacteria carrying 2 identical chromosomes differing only in their respective cblA allele, (c) partially diploid bacteria due to partial deletion from the 2nd chromosome with the chromosomes differing in their respective cblA allele, the gene content and synteny.
