Figure 3 | Scientific Reports

Figure 3

From: Immune cell-derived cytokines contribute to obesity-related inflammation, fibrogenesis and metabolic deregulation in human adipose tissue

Figure 3

Cytokine-specific effect on fibrotic and inflammatory genes. Principal components analysis (PCA) plots of fibrotic and inflammatory genes in pre-adipocytes (A) and CD31+ endothelial cells (B) treated or not by rIL-17 (10 ng/mL), rIL-1β (10 ng/mL) or rTGF-β1 (5 ng/mL). Points represent individual cell cultures in untreated control (Ctr) or cytokine-treated conditions as indicated. Groups are identified by color and circled with a median elliptical centroid. Arrows depict the contribution of each gene to sample coordinates. P values were obtained by Monte Carlo rank test.

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