Table 2 Relative binding affinity, analyzed by MS competition assay for un2, un3, gp054a, hTel21, c-kit2 (kit), c-myc (myc) and HIV-1 LTR-III G4-folded oligonucleotides.

From: A core extended naphtalene diimide G-quadruplex ligand potently inhibits herpes simplex virus 1 replication

Binding affinity c-exNDI19

Competing G4s

un2

un3

gp054a

LTR-III

Cell (hTel/myc/kit)

un2/LTR-III

20

  

58

 

un2/kit

24

   

46

un2/myc

15

   

68

un2/hTel

34

   

30

un3/LTR-III

 

43

 

61

 

un3/kit

 

52

  

31

un3/myc

 

36

  

66

un3/hTel

 

72

  

21

gp054a/LTR-III

  

3

75

 

gp054a/kit

  

7

 

64

gp054a/myc

  

4

 

78

gp054a/hTel

  

12

 

39

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