Table 2 List of miRNA populations differentially expressed after EDCs exposure.

From: Chronic low-dose exposure to a mixture of environmental endocrine disruptors induces microRNAs/isomiRs deregulation in mouse concomitant with intratesticular estradiol reduction

ID

Control

Mixture of EDCs

Fold-change (log2)

Differential expression

% of total identified reads

% of total identified reads

pre-mir-34b (*)

2.3903

3.7084

0.5025

Up

pre-mir-15b (*)

0.2256

0.1676

−0.5599

Down

pre-mir-1291 (*)

0.0052

0.0020

−1.5419

Down

pre-mir-378b (*)

0.0049

0.0017

−1.6123

Down

miR-7686-5p

0.0007

0.0038

2.3565

Up

miR-34b-5p (*)

1.8976

3.1490

0.5968

Up

miR-18a-5p

0.0371

0.0277

−0.5548

Down

miR-15b-5p (*)

0.2152

0.1596

−0.5656

Down

miR-1981-5p

0.0578

0.0311

−1.0274

Down

miR-382-5p

0.0049

0.0023

−1.2120

Down

miR-20b-5p

0.0042

0.0019

−1.2874

Down

miR-1291 (*)

0.0047

0.0019

−1.4509

Down

miR-378b (*)

0.0047

0.0017

−1.6208

Down

miR-3085-3p

0.0024

0.0004

−2.6208

Down

  1. Table shows differentially expressed testicular precursors and canonical miRNAs in control and chronically exposed animals to the mixture of EDCs. (*) The asterisk indicates increase or decrease in both the precursor and the mature form of the miRNA. RNA libraries of pools of mice testes, fold change (log2). Data normalised using the DeSeq tool of the R/Bioconductor software package, n = 3, *p ≤ 0.05.