Figure 2
From: Thalamic Bursts Down-regulate Cortical Theta and Nociceptive Behavior
TRN stimulation decreases SI power in the theta band while increasing thalamic bursts and withdrawal threshold in naive VGAT mice. (a) Histogram showing the effects of TRN stimulation at 0.5, 10 and 50 Hz on mean theta (4–8 Hz) power under 1.5% isoflurane sedation (n = 2 mice). (b) SI power spectra. Inset in right panel shows significant decrease in power within the theta band (3.8–8.5 Hz) following 10 Hz TRN stimulation in awake mice (n = 5 mice). (c) TRN stimulation increases burst firing in VPL neurons (n = 17 units, 3–4 units per mouse; 5 mice) and increases the threshold of mechanical withdrawal to von Frey stimuli (d; n = 4 mice).
