Table 1 bCSC specific Transcription Factors and Master Regulator.

From: Transcription Factor Networks derived from Breast Cancer Stem Cells control the immune response in the Basal subtype

Genes

Mode

FET P-Value

bCSC/CC

bCSC/Bulk

IKZF3

-

4.60E-152

−7.67

−2.46

SCML4

-

4.49E-147

−4.34

−6.62

SP140

-

9.48E-145

−7.89

−2.66

ZNF831

-

1.74E-138

−5.98

−2.02

BNC2

+

7.24E-22

3.76

2.13

HOXA5

+

4.37E-20

2.74

3.02

PRRX1

+

2.42E-18

7.31

3.22

SNAI2

+

1.23E-12

6.47

2.93

TBX5

+

8.01E-10

2.87

5

TWIST1

+

3.34E-09

5.05

3.31

ID4

+

9.06E-09

3.9

2.38

  1. The 11 transcription factors differentially expressed and with the same pattern, up or down regulated, in both “bCSC/Bulk” and “bCSC/CC” datasets and selected as master regulators in the “bCSC/CC” dataset by MRA-FET. Mode = Positively (+) or negatively (−) correlated with the bCSC phenotype, FET p-Values = P value as possible Master regulator in MRA-FET analysis, bCSC/CC = Fold Change in the bCSC/CC dataset of the determined gene, bCSC/Bulk = Fold Change in the bCSC/Bulk dataset of the determined gene.
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