Figure 4

Proliferation and differentiative potential of diploid and tetraploid ESCs. (A) Proliferation of diploid and tetraploid ESCs. (B) Cell diameter of diploid and tetraploid ESCs. (C) FACS analysis of cell cycle differences between diploid and tetraploid ESCs. (D) Relative mRNA expression levels of cell division-related genes in diploid and tetraploid ESCs. (E) Relative mRNA expression levels of three germ layer and trophectoderm genes in 3 d and 5 d diploid and tetraploid EBs. Different superscripts represent statistically significant differences between groups (P < 0.05).