Table 3 One way ANOVA results at P < 0.05 for Cmax and AUC0-inf after administration of 25 mg empagliflozin in Japanese11 and Chinese subjects9.

From: Pharmacokinetic Evaluation of Empagliflozin in Healthy Egyptian Volunteers Using LC-MS/MS and Comparison with Other Ethnic Populations

Cmax (nMol/L)

AUC0-inf (nMol.h/L)

Groups

Number of subjects

Mean

S.D., (% CV)

Mean

S.D., (% CV)

*Group 111

8

1070

193.7, (18.1)

7560

1126.4, (14.9)

*Group 29

9

1130

318.7, (28.2)

7450

1959, (26.3)

  1. *Studied groups from pharmacokinetic studies conducted in Japanese11 and Chinese9 subjects using 25 mg empagliflozin showed no significant difference at P > 0.05, with P = 0.651 for Cmax and P = 0.891 for AUC0-inf.
  2. Abbreviations: AUC = area under the curve; % C.V. = percent coefficient of variation; S.D. = standard deviation.
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