Table 2 Antibacterial activity: diameter of the inhibition zone (in mm) surrounding the azetidinone-HA samples against S. aureus and E. coli strains.

From: Monocyclic β-lactams loaded on hydroxyapatite: new biomaterials with enhanced antibacterial activity against resistant strains

Sample

β-lactam content wt %

S. aureus ATCC 25923

E. coli ATCC 25922

1a-HA

8.1

30 ± 1

27 ± 1

1b-HA

17.0

27 ± 1

12 ± 1

2a-HA

14.0

20 ± 1

14 ± 1

2b-HA

16.5

16 ± 1

11 ± 1

HAa

 

NAb

NAb

GMNc

 

18 ± 1

19 ± 1

  1. aPure HA disks were used as negative controls. bBacterial-free zone not appearing.
  2. cDisks containing gentamicin 10 µg (Oxoid SpA, Italy) were used as positive controls.
  3. All experiments were performed on triplicate, on three different days.
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