Table 1 The mean and SD of multi-parametric MRI parameters for the femoral and tibial subchondral bone marrow.
Week 0 | Week 8 | Week 12 | Week 16 | Week 24 | Week 30 | Week 36 | Week 44 | |||
---|---|---|---|---|---|---|---|---|---|---|
Mean ± SD | Mean ± SD | Mean ± SD | Mean ± SD | Mean ± SD | Mean ± SD | Mean ± SD | Mean ± SD | |||
Control | Femoral | A | 0.543 ± 0.054 | 0.543 ± 0.057 | 0.537 ± 0.054 | 0.504 ± 0.082 | 0.529 ± 0.069 | 0.527 ± 0.073 | 0.499 ± 0.062 | 0.474 ± 0.057 |
k el | 0.436 ± 0.027 | 0.432 ± 0.020 | 0.434 ± 0.019 | 0.437 ± 0.017 | 0.429 ± 0.025 | 0.422 ± 0.038 | 0.397 ± 0.033 | 0.398 ± 0.037 | ||
k ep | 7.425 ± 0.591 | 7.627 ± 0.470 | 7.810 ± 0.474 | 7.737 ± 0.550 | 7.945 ± 0.617 | 8.168 ± 0.326 | 7.913 ± 0.873 | 7.795 ± 0.417 | ||
FF | 0.134 ± 0.056 | 0.484 ± 0.077 | 0.528 ± 0.039 | 0.534 ± 0.046 | 0.532 ± 0.046 | 0.553 ± 0.060 | 0.619 ± 0.075 | 0.575 ± 0.091 | ||
WF | 0.866 ± 0.055 | 0.516 ± 0.035 | 0.472 ± 0.081 | 0.466 ± 0.046 | 0.468 ± 0.064 | 0.447 ± 0.083 | 0.381 ± 0.058 | 0.425 ± 0.091 | ||
T2* | 11.05 ± 1.122 | 11.53 ± 1.361 | 11.88 ± 1.008 | 11.47 ± 1.101 | 11.20 ± 1.018 | 11.93 ± 1.643 | 11.75 ± 1.492 | 12.88 ± 1.639 | ||
Tibial | A | 0.465 ± 0.084 | 0.467 ± 0.074 | 0.434 ± 0.063 | 0.421 ± 0.082 | 0.435 ± 0.053 | 0.424 ± 0.083 | 0.441 ± 0.090 | 0.380 ± 0.061 | |
k el | 0.420 ± 0.021 | 0.423 ± 0.042 | 0.418 ± 0.030 | 0.420 ± 0.021 | 0.420 ± 0.025 | 0.411 ± 0.026 | 0.392 ± 0.036 | 0.379 ± 0.048 | ||
k ep | 7.493 ± 0.970 | 7.580 ± 0.983 | 7.743 ± 0.871 | 7.950 ± 0.547 | 7.952 ± 0.548 | 7.948 ± 0.544 | 7.810 ± 0.699 | 7.903 ± 0.393 | ||
FF | 0.127 ± 0.056 | 0.421 ± 0.142 | 0.492 ± 0.099 | 0.492 ± 0.084 | 0.493 ± 0.126 | 0.546 ± 0.110 | 0.519 ± 0.074 | 0.562 ± 0.060 | ||
WF | 0.873 ± 0.044 | 0.579 ± 0.071 | 0.508 ± 0.084 | 0.508 ± 0.091 | 0.507 ± 0.081 | 0.454 ± 0.046 | 0.481 ± 0.080 | 0.438 ± 0.081 | ||
T2* | 10.88 ± 1.338 | 10.56 ± 1.337 | 10.94 ± 0.572 | 10.54 ± 1.148 | 11.69 ± 1.089 | 11.45 ± 0.862 | 11.69 ± 1.741 | 12.29 ± 1.029 | ||
CKD | Femoral | A | 0.701 ± 0.073 | 0.515 ± 0.041 | 0.430 ± 0.064 | 0.397 ± 0.086 | 0.347 ± 0.074 | 0.333 ± 0.085 | 0.344 ± 0.069 | 0.261 ± 0.087 |
k el | 0.429 ± 0.046 | 0.416 ± 0.035 | 0.383 ± 0.039 | 0.374 ± 0.036 | 0.359 ± 0.034 | 0.362 ± 0.026 | 0.333 ± 0.024 | 0.296 ± 0.038 | ||
k ep | 7.698 ± 0.470 | 7.658 ± 0.796 | 8.038 ± 0.742 | 8.173 ± 0.547 | 8.200 ± 0.518 | 7.707 ± 0.486 | 9.152 ± 0.476 | 9.587 ± 1.081 | ||
FF | 0.109 ± 0.068 | 0.379 ± 0.081 | 0.341 ± 0.122 | 0.359 ± 0.086 | 0.355 ± 0.074 | 0.344 ± 0.093 | 0.297 ± 0.092 | 0.275 ± 0.086 | ||
WF | 0.891 ± 0.045 | 0.621 ± 0.129 | 0.659 ± 0.086 | 0.641 ± 0.085 | 0.645 ± 0.091 | 0.656 ± 0.075 | 0.703 ± 0.075 | 0.725 ± 0.060 | ||
T2* | 11.41 ± 1.185 | 11.16 ± 0.892 | 12.35 ± 1.013 | 13.51 ± 1.299 | 15.76 ± 1.802 | 16.39 ± 2.093 | 16.31 ± 1.896 | 16.68 ± 1.386 | ||
Tibial | A | 0.618 ± 0.077 | 0.429 ± 0.035 | 0.295 ± 0.082 | 0.264 ± 0.072 | 0.252 ± 0.066 | 0.276 ± 0.064 | 0.274 ± 0.045 | 0.204 ± 0.072 | |
k el | 0.428 ± 0.033 | 0.402 ± 0.022 | 0.381 ± 0.031 | 0.380 ± 0.020 | 0.346 ± 0.040 | 0.345 ± 0.035 | 0.317 ± 0.036 | 0.290 ± 0.057 | ||
k ep | 7.442 ± 0.821 | 7.775 ± 0.441 | 8.005 ± 0.898 | 8.018 ± 1.009 | 8.280 ± 0.965 | 8.485 ± 0.966 | 8.882 ± 0.883 | 9.417 ± 0.865 | ||
FF | 0.104 ± 0.062 | 0.297 ± 0.077 | 0.329 ± 0.084 | 0.324 ± 0.085 | 0.315 ± 0.065 | 0.285 ± 0.053 | 0.266 ± 0.077 | 0.259 ± 0.087 | ||
WF | 0.896 ± 0.021 | 0.703 ± 0.129 | 0.671 ± 0.073 | 0.676 ± 0.116 | 0.685 ± 0.092 | 0.715 ± 0.109 | 0.734 ± 0.139 | 0.741 ± 0.136 | ||
T2* | 11.20 ± 1.359 | 11.15 ± 1.429 | 11.61 ± 1.402 | 13.48 ± 1.356 | 15.03 ± 1.578 | 15.12 ± 1.972 | 15.88 ± 1.933 | 16.01 ± 1.844 |