Figure 2 | Scientific Reports

Figure 2

From: Human dimethylarginine dimethylaminohydrolase 1 inhibition by proton pump inhibitors and the cardiovascular risk marker asymmetric dimethylarginine: in vitro and in vivo significance

Figure 2

Concentration dependent inhibition of DDAH1 by ZST316 (positive control), esomeprazole (EPZ), lansoprazole (LPZ), omeprazole (OPZ), pantoprazole (PPZ) and rabeprazole (RPZ). Residual DDAH1 activity is reported as percentage of control activity. Each data point represents the mean of at least two single experiments. Error bars represent the standard deviation. *P < 0.01 for trend; #P < 0.05 vs. baseline; ^P < 0.01 vs. baseline.

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