Figure 4

Detection of rabeprazole (RPZ) degradation products. UV chromatograms detected at 280 nm for pantoprazole (PPZ) and RPZ at time 0 (A and B, respectively), after 30 min of incubation (C and D, respectively) and after 4 h of incubation (E and F, respectively). Additional peaks in RPZ chromatograms are attributed to RPZ degradation products and were identified using published mass spectral data17 (data not shown). The arrow indicates the residual peak for RPZ.