Table 5 Relationships of total testosterone with adiponectin and leptin levels.

From: Lower SHBG level is associated with higher leptin and lower adiponectin levels as well as metabolic syndrome, independent of testosterone

Log10 Adiponectin

N

Mean ± SD

Model 1

Model 2

Model 3

ß (SE)

p-value

ß (SE)

p-value

ß (SE)

p-value

Total testosterone (ng/dl)

614

390.6 ± 97.1

0.125 (<0.001)

0.002

0.021 (<0.001)

0.613

0.017 (<0.001)

0.675

0–25th

153

273.2 ± 35.6

Ref

—

Ref

—

Ref

—

25–50th

154

351.1 ± 19.5

0.070 (0.028)

0.150

0.037 (0.027)

0.437

0.036 (0.027)

0.436

50–75th

154

418.2 ± 20.3

0.153 (0.028)

0.002

0.095 (0.028)

0.045

0.099 (0.027)

0.036

>75th

153

518.7 ± 54.6

0.135 (0.028)

0.006

0.016 (0.029)

0.748

0.014 (0.028)

0.781

P for trend

   

0.002

 

0.480

 

0.485

Log 10 Leptin

N

Mean ± SD

ß (SE)

p-value

ß (SE)

p-value

ß (SE)

p-value

Total testosterone (ng/dl)

614

390.6 ± 97.1

−0.169 (<0.001)

<0.001

−0.114 (<0.001)

0.007

−0.105 (<0.001)

0.01

0–25th

153

273.2 ± 35.6

Ref

—

Ref

—

Ref

—

25–50th

154

351.1 ± 19.5

−0.025 (0.028)

0.617

−0.005 (0.028)

0.915

−0.005 (0.027)

0.920

50–75th

154

418.2 ± 20.3

−0.152 (0.028)

0.002

−0.119 (0.028)

0.016

−0.129 (0.027)

0.006

>75th

153

518.7 ± 54.6

−0.148 (0.028)

0.003

−0.080 (0.029)

0.124

−0.074 (0.028)

0.132

P for trend

   

<0.001

 

0.029

 

0.023

  1. Abbreviation: SD = standard deviation; SE = standard error; OR = odds ratio; CI = confidence interval.
  2. Model 1: adjusted for age, educational level, alcohol drinking, and cigarette smoking.
  3. Model 2: Model 1 plus sexual hormone binding globulin level.
  4. Model 3: Model 2 plus body mass index.