Figure 4

Serum anti-HBc holds a better diagnostic value for differentiating between mild or no (HAI < 5) and moderate-to-severe (HAI ≥ 5) in HBeAg (+) (a) and HBeAg (−) (b) patents with normal ALT. AUROC, area under receiver operating characteristics curve; GGT, gamma glutamyl transpeptidase; AST, aspartate aminotransferase; Se, sensitivity; Spe, specificity; PPV, positive predictive value; NPV, negative predictive value.