Table 2 Correlation between histology activity index score and anti-HBc levels, ALT levels according to the ALT stratum.

From: Serum hepatitis B core antibody as a biomarker of hepatic inflammation in chronic hepatitis B patients with normal alanine aminotransferase

 

Correction

ALT stratum (Spearman’r; P value)

ALT < 1 × ULN

1 × ULN < ALT < 2 × ULN

ALT > 2 × ULN

HBeAg + (404)

ALT vs. anti-HBc

0.044; 0.66

0.138; 0.08

0.250; <0.01

ALT vs. HAI

0.126; 0.21

0.122; 0.12

0.207; 0.01

anti-HBc vs. HAI

0.617; <0.001

0.427; <0.001

0.263; <0.01

HBeAg− (251)

ALT vs. anti-HBc

0.191; 0.06

0.195; 0.06

0.219; 0.03

ALT vs. HAI

0.156; 0.13

0.080; 0.46

0.311; <0.01

anti-HBc vs. HAI

0.378; <0.001

0.428; <0.001

0.232; 0.06

  1. ALT, alanine aminotransferase; HBeAg, hepatitis B e antigen ULN, upper limit of normal; HAI, histology activity index.