Figure 6
Effects of LPS on INa. (A) Representative traces of INa at −30 mV in absence and presence of 20 µM TTX. (B) Averaged peak INa at −30 mV in control and LPS-treated hiPSC-CMs. (C) Averaged values of late INa at −30 mV. (D) Representative activation curves of peak INa. (E) Representative inactivation curves of peak INa. (F) Representative curves of recovery from inactivation of peak INa. (G) Mean values of voltages at 50% of steady-state activation of peak INa (V0.5). (H) Mean values of voltages at 50% of steady-state inactivation of peak INa. (I) Mean values of time constants (Tau) of recovery from inactivation of peak INa. Values given are mean ± SEM. n, number of cells. *p < 0.05.
