Table 2 Stratified analysis of rs7958904 genotypes and CC risk by selected variables.
Variables | GG/GC (cases/control) | CC (cases/control) | P | Adjusted OR (95% CI)a | ||
---|---|---|---|---|---|---|
n | % | n | % | |||
All | 1067/1229 | 92.5/95.1 | 86/63 | 7.5/4.9 | 0.008 | 1.57 (1.10–2.25) |
Age (years) | ||||||
≤49 | 570/632 | 93.1/6.9 | 42/32 | 95.2/4.8 | 0.119 | 1.45 (0.89–2.37) |
>49 | 497/597 | 91.9/95.1 | 44/31 | 8.1/4.9 | 0.026 | 1.70 (1.00–2.88) |
Parity | ||||||
0–1 | 607/960 | 92.7/95.1 | 48/49 | 7.3/4.9 | 0.036 | 1.60 (1.05–2.46) |
≥2 | 450/238 | 92.4/94.8 | 37/13 | 7.6/5.2 | 0.216 | 1.47 (0.76–2.82) |
Abortion | ||||||
No | 353/349 | 91.2/94.6 | 34/20 | 8.8/5.4 | 0.073 | 1.41 (0.75–2.66) |
Yes | 669/751 | 93.3/95.6 | 48/35 | 6.7/4.4 | 0.057 | 1.73 (1.07–2.80) |
Menopausal status | ||||||
Premenopausal | 605/648 | 92.9/95.3 | 46/32 | 7.1/4.7 | 0.067 | 1.51 (0.94–2.44) |
Postmenopausal | 458/490 | 92.0/95.3 | 40/24 | 8.0/4.7 | 0.028 | 1.64 (0.95–2.84) |
Depth of invasion | ||||||
I | 710/1229 | 93.5/95.1 | 49/63 | 6.5/4.9 | 0.129 | 1.30 (0.86–1.96) |
II | 314/1229 | 90.8/95.1 | 32/63 | 9.2/4.9 | 0.002 | 2.06 (1.29–3.31) |
III/IV | 31/1229 | 88.6/95.1 | 4/63 | 11.4/4.9 | 0.081 | 2.42 (0.81–7.21) |