Table 2 Stratified analysis of rs7958904 genotypes and CC risk by selected variables.

From: HOTAIR rs7958904 polymorphism is associated with increased cervical cancer risk in a Chinese population

Variables

GG/GC (cases/control)

CC (cases/control)

P

Adjusted OR (95% CI)a

n

%

n

%

All

1067/1229

92.5/95.1

86/63

7.5/4.9

0.008

1.57 (1.10–2.25)

Age (years)

 ≤49

570/632

93.1/6.9

42/32

95.2/4.8

0.119

1.45 (0.89–2.37)

 >49

497/597

91.9/95.1

44/31

8.1/4.9

0.026

1.70 (1.00–2.88)

Parity

 0–1

607/960

92.7/95.1

48/49

7.3/4.9

0.036

1.60 (1.05–2.46)

 ≥2

450/238

92.4/94.8

37/13

7.6/5.2

0.216

1.47 (0.76–2.82)

Abortion

 No

353/349

91.2/94.6

34/20

8.8/5.4

0.073

1.41 (0.75–2.66)

 Yes

669/751

93.3/95.6

48/35

6.7/4.4

0.057

1.73 (1.07–2.80)

Menopausal status

 Premenopausal

605/648

92.9/95.3

46/32

7.1/4.7

0.067

1.51 (0.94–2.44)

 Postmenopausal

458/490

92.0/95.3

40/24

8.0/4.7

0.028

1.64 (0.95–2.84)

Depth of invasion

 I

710/1229

93.5/95.1

49/63

6.5/4.9

0.129

1.30 (0.86–1.96)

 II

314/1229

90.8/95.1

32/63

9.2/4.9

0.002

2.06 (1.29–3.31)

 III/IV

31/1229

88.6/95.1

4/63

11.4/4.9

0.081

2.42 (0.81–7.21)

  1. aAdjusted for age, parity, and menopausal status in logistic regression model.