Figure 2 | Scientific Reports

Figure 2

From: Synthesis, Chemical Characterization and Multiscale Biological Evaluation of a Dimeric-cRGD Peptide for Targeted Imaging of α V β 3 Integrin Activity

Figure 2

SPR sensograms depicting binding between cRGD ligands and α V β 3 integrin receptor. BIAcore 3000 kinetics studies of interactions between immobilized integrin α V β 3 receptor and (A) monomeric cyclic RGD probe (NOTA-cRGD), (B) dimeric cyclic RGD (NOTA-PEG4-cRGD2) probe, (C) cRGD2 conjugated with FITC (FITC-PEG4-cRGD2), and (D) NOTA-PEG4-cRGD2 labeled with non-radioactive Cu2+. Kinetic studies were performed at a 30 μ L/min flow rate, with a 4 min association followed by a 10 min dissociation period.

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